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Search Results (53)

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MatchTypeWhy
BRCA1 ProteinConcept Why?
Neddylation of a breast cancer-associated protein recruits a class III histone deacetylase that represses NFkappaB-dependent transcription.Academic Article Why?
Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness.Academic Article Why?
Characterization of the Cancer Spectrum in Men With Germline BRCA1 and BRCA2 Pathogenic Variants: Results From the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA).Academic Article Why?
Complete Remission Following Pembrolizumab in a Woman with Mismatch Repair-Deficient Endometrial Cancer and a Germline BRCA1 Mutation.Academic Article Why?
Evaluation of the relative effectiveness of the 2017 updated Manchester scoring system for predicting BRCA1/2 mutations in a Southeast Asian country.Academic Article Why?
MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers.Academic Article Why?
Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations.Academic Article Why?
Phase I dose escalation study of the PI3kinase pathway inhibitor BKM120 and the oral poly (ADP ribose) polymerase (PARP) inhibitor olaparib for the treatment of high-grade serous ovarian and breast cancer.Academic Article Why?
Wolfe, AdamPerson Why?
ZMYM2 restricts 53BP1 at DNA double-strand breaks to favor BRCA1 loading and homologous recombination.Academic Article Why?
ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.Academic Article Why?
Efflux transporter breast cancer resistance protein dominantly expresses on the membrane of red blood cells, hinders partitioning of its substrates into the cells, and alters drug-drug interaction profiles.Academic Article Why?
A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers.Academic Article Why?
BRCA1 expression and improved survival in ovarian cancer patients treated with intraperitoneal cisplatin and paclitaxel: a Gynecologic Oncology Group Study.Academic Article Why?
Modification of BRCA1-Associated Breast and Ovarian Cancer Risk by BRCA1-Interacting Genes.Academic Article Why?
Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers.Academic Article Why?
Wiesner Nevus of the Eyelid.Academic Article Why?
Birrer, MichaelPerson Why?
BRCA1 and FOXA1 proteins coregulate the expression of the cell cycle-dependent kinase inhibitor p27(Kip1).Academic Article Why?
BRCA1 transactivates the cyclin-dependent kinase inhibitor p27(Kip1).Academic Article Why?
Characteristics of individuals with breast cancer rearrangements in BRCA1 and BRCA2.Academic Article Why?
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.Academic Article Why?
Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2.Academic Article Why?
Persistent Activation of NF-?B in BRCA1-Deficient Mammary Progenitors Drives Aberrant Proliferation and Accumulation of DNA Damage.Academic Article Why?
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